Looking for Regional Information?

IUI (Intrauterine insemination) Treatment

By Dr.Arjun Bhojwani Published 02/12/2007 | Health

Until now, getting infertility treatment of any kind in USA was too costly for most people. Today the world's getting smaller and travel is easier. You have options. Have you heard the latest? People are flying to India and getting their treatment done. Not only do you get your treatment for a fraction of the cost, but you get to travel to exotic India too. For last few years India has been depicting its proficiency in medical treatment packages. The major USP of medical tourism India is its cut-throat price of the treatment packages.

What is IUI (Intrauterine insemination)?

Intrauterine insemination (IUI) is the process of preparing a sperm specimen to concentrate it for the most active motile sperm and placing the washed sperm into the uterus as close as possible to the tubal opening. Intrauterine insemination is often recommended because studies have shown that pregnancy is more likely to occur if timing of exposure to sperm is controlled, and if sperm is placed in higher numbers closer to the egg or eggs.

Who might benefit from insemination?  

There are selected groups of patients to whom sperm donation is recommended.

  • Men who are unable to ejaculate inside their wifes vagina for whatever reasons. This is the classical indication. Causes for ejaculation failure include diabetes, multiple sclerosis, spinal cord injury and retrograde ejaculation, where sperm are released backward into the bladder instead of urethra. Retrograde ejaculation may be due to diabetes, trauma or operation in the bladder neck or a side effect of certain drugs.
  • Men with mildly low sperm count, poor quality sperm or antisperm antibodies.
  • Men who wish to freeze their sperm for possible future use before vasectomy, chemotherapy or radiotherapy for cancer.
  • Women with mild endometriosis.
  • Women with cervical mucus hostility or poor cervical mucus.
  • Couples with unexplained infertility.
  • Some infertility clinics may offer intrauterine insemination of a HIV negative woman with washed and prepared sperm of her HIV positive husband/partner.

When is the best timing for an IUI?

 Ideally an IUI should be performed within 6 hours either side of ovulation for male factor infertility some doctors believe after ovulation is better, otherwise chances of success are higher with insemination before ovulation with the sperm waiting for the egg. When timing is based on an HCG injection, the IUIs are usually done between 24 and 48 hours later. Typical timing would be to have a single IUI at about 36 hours post-hCG, though some do it at 24 hours, and some clinics are reporting better results when doing the IUI at 40-42 hours post-hCG. If two IUIs are scheduled, they are usually spaced at least 12 hours apart between 24 and 48 hours after the hCG. Some reports show no increase in success rates with two IUIs, but others suggest it may increase success as much as 6 percent. Some doctors will base timing of IUI on a natural LH surge. In that case, a single IUI at 36 hours is the norm, but doing them at 24 hours is also pretty common since ovulation may be a bit earlier. When two inseminations are planned, they are usually timed between 12 and 48 hours after the surge is detected. The egg is only viable for a maximum of 24 hours after it is released.

The process of intrauterine insemination:

Insemination is normally carried out when one is nearing the ovulation cycle. Medication is used to stimulate a woman to produce multiple eggs. While the semen is procured from the male who has brought a specimen from home or is made to masturbate in the clinic. The semen has to be produced after 2-5 days of abstaining from ejaculation.

Next the washing of the semen is carried out. Here the sperm is separated from the other fluids and kept as a concentrated component. Sperm washing takes fifteen minutes to an hour depending on the case and the technique used by the clinic.

Now with one component ready, a soft catheter is used to insert the sperm in the cervix of the woman or in the uterine cavity. The woman is required to lie down during this process although the position is not proved to better pregnancy.

With the onset of ovulation, intrauterine insemination has to be conducted within 6 hours. If the male is known to be infertile IUI after ovulation is thought to be purposeful. If it is based on the hCG injection then IUI is done 24 to 48 hours later. Sometimes two IUI can also be conducted. In this case there has to be a break of 12 hours between the first and the second.

What is the success rate of IUI treatment?

The success rate of IUI depends upon several factors. First of all the cause of the infertility problem is important. For example, men with normal sperm counts who are unable to have intercourse have a much higher chance of success than patients who are undergoing IUI for poor sperm counts. In addition, female factors play an important role. If the female is more than 35, the chance of a successful pregnancy is significantly decreased. Generally, the chance of conceiving in one cycle is about 10-15%; and the cumulative conception rate is about 50% over 4 treatment cycles. (Remember, Nature's efficiency for producing a baby in one month is about 15 to 25 %). However, if IUI is going to work for a couple, it usually does so within 4 treatment cycles. If a pregnancy has not resulted by this time, the chances of IUI working for you are very remote. You have reached the point of diminishing returns, and should stop persisting with IUI and explore the option of IVF.

IUI (Intrauterine insemination) treatment in India:             

India has a talent pool of qualified doctors, a lot of whom have been trained in the US and UK, in specialized areas of infertility treatment. With the recent development of the healthcare infrastructure in India, the best of facilities and equipment are also available with these doctors. This coupled with the extremely low cost of the treatments makes India the ideal destination for your infertility treatment needs.

To know more about Hospitals in India and the Intrauterine insemination (IUI treatment packages available in Hospitals,

Please visit- http://www.fly2india4health.com

Important Details:

Medical Tourism to India -



International Patient Experiences-http://www.fly2india4health.com/international.php

Email -[email protected]